Your body interacts with microorganisms in multiple locations in the body symbiotically, and this relationship is particularly important in the intestinal tract. Microorganisms residing in the intestinal tract are collectively called the gut microbiota. They provide us with numerous benefits, including helping to break down nutrients you otherwise would not be able to obtain. It has also been found that the gut microbiome may be involved in regulating functions normally associated with the brain through the gut-brain axis. This has been supported by studies that have found evidence linking the gut microbiota to disorders such as autism and depression. A recent study also suggests that anxiety may be affected by the bacteria living in our guts.

Cartoon depiction of gut bacteria.

Cartoon depiction of the various bacteria in our guts.

Image Source: jamesbenet

Researchers from Shanghai Jiao Tong University School of Medicine have found that both probiotic and non-probiotic interventions targeting the microbiome may help reduce symptoms associated with anxiety. Probiotics refer to products, such as yogurt or pills, containing microorganisms that are commonly found living within us. Probiotics have been shown to have many benefits, particularly for individuals with chronic conditions that affect their gut microbiome, such as lactose intolerance. Non-probiotic interventions refer to other strategies such as changing one’s diet. Both are capable of altering our body’s microbiome, but the degree to which they do so is arguable. Nevertheless, the researchers found that over half of their 21 studies showed a measurable reduction in participants’ anxiety after the usage of probiotic interventions, and even more so after non-probiotic interventions.

Probiotic supplements can come in the form of pills. 

Probiotics often come in the form of pills such as these.

Image Source: Douglas Sacha

These findings suggest that anxiety may be regulated by our gut microbiome. The researchers recognize, however, that potential implications are limited due to this being an observational study. Further studies, especially ones that could uncover the underlying mechanisms behind how bacteria in our intestines can cause anxiety symptoms, will need to be performed before one can expect providers to prescribe probiotics for anxiety.

Featured Image Source: Maridav

Raymond Ho

Author Raymond Ho

Raymond is a fourth year student at UC Berkeley majoring in Molecular and Cell Biology and is interested in the therapeutic applications of basic science.

More posts by Raymond Ho